Original Articles Differentiation of Human Embryonic Stem Cells into Embryoid Bodies Comprising the Three Embryonic Germ Layers

نویسندگان

  • Joseph Itskovitz-Eldor
  • Maya Schuldiner
  • Dorit Karsenti
  • Amir Eden
  • Ofra Yanuka
  • Michal Amit
  • Hermona Soreq
  • Nissim Benvenisty
چکیده

rived from totipotent cells of the embryo and therefore, can serve as a putative source of numerous types of differentiated cells. Of the various ES cell lines, murine (mES) cells have been investigated extensively and were shown to be genuinely pluripotent, being able to differentiate into all embryonic cell types (1,2). The multipotency of embryonic stem cells is evident from three main features: (A) These undifferentiated cells can be injected into the blastocyst cavity Molecular Medicine 6(2): 88–95, 2000

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تاریخ انتشار 1999